Post-sympathectomy neuralgia: hypotheses on peripheral and central neuronal mechanisms.

@article{Kramis1996PostsympathectomyNH,
  title={Post-sympathectomy neuralgia: hypotheses on peripheral and central neuronal mechanisms.},
  author={R C Kramis and William J Roberts and Richard G Gillette},
  journal={Pain},
  year={1996},
  volume={64 1},
  pages={1-9}
}
Post-sympathectomy neuralgia is proposed here to be a complex neuropathic and central deafferentation/reafferentation syndrome dependent on: (a) the transection, during sympathectomy, of paraspinal somatic and visceral afferent axons within the sympathetic trunk; (b) the subsequent cell death of many of the axotomized afferent neurons, resulting in central deafferentation; and (c) the persistent sensitization of spinal nociceptive neurons by painful conditions present prior to sympathectomy… CONTINUE READING

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