Post-infarct cortical plasticity and behavioral recovery using concurrent cortical stimulation and rehabilitative training: a feasibility study in primates.

@article{Plautz2003PostinfarctCP,
  title={Post-infarct cortical plasticity and behavioral recovery using concurrent cortical stimulation and rehabilitative training: a feasibility study in primates.},
  author={Erik Jon Plautz and Scott Barbay and Shawn Frost and Kathleen Friel and Numa Dancause and Elena V. Zoubina and Ann M Stowe and Barbara Marie Quaney and Randolph J. Nudo},
  journal={Neurological research},
  year={2003},
  volume={25 8},
  pages={
          801-10
        }
}
Stroke is often characterized by incomplete recovery and chronic motor impairments. A nonhuman primate model of cortical ischemia was used to evaluate the feasibility of using device-assisted cortical stimulation combined with rehabilitative training to enhance behavioral recovery and cortical plasticity. Following pre-infarct training on a unimanual motor task, maps of movement representations in primary motor cortex were derived. Then, an ischemic infarct was produced which destroyed the hand… CONTINUE READING
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