Post-hypophysectomy ovarian senescence and its relation to the spontaneous structural changes in the ovary of intact aged rats.

@article{CrumeyrolleArias1981PosthypophysectomyOS,
  title={Post-hypophysectomy ovarian senescence and its relation to the spontaneous structural changes in the ovary of intact aged rats.},
  author={Mich{\`e}le Crumeyrolle-Arias and Pierre Aschheim},
  journal={Gerontology},
  year={1981},
  volume={27 1-2},
  pages={58-71}
}
Hypophysectomy performed in 25- to 26-day-old Wistar rats leads within 1 years to the formation of ovarian testis-like tubes and epithelial cellular cords which are typical structures in the senile ovaries of normal 24-month-old rats. Testis-like tubes represent an unusual late stage of follicular degeneration; the origin of the cords is more complex; the… CONTINUE READING