Post-chemotherapy T-cell recovery is a marker of improved survival in patients with advanced thoracic malignancies

@inproceedings{McCoy2012PostchemotherapyTR,
  title={Post-chemotherapy T-cell recovery is a marker of improved survival in patients with advanced thoracic malignancies},
  author={Melanie J McCoy and Richard A. Lake and Robbert G. van der Most and Ian Dick and Anna K. Nowak},
  booktitle={British Journal of Cancer},
  year={2012}
}
Background:There is increasing interest in combining chemotherapy with immunotherapy. However, the effects of chemotherapy on the human immune system are largely unknown.Methods:Longitudinal changes in peripheral T-cell subsets in 40 patients with malignant mesothelioma (MM) or advanced non-small cell lung cancer (NSCLC) receiving platinum-based chemotherapy were assessed by flow cytometry and evaluated for associations with clinical outcome.Results:Proliferating T cells of all subsets were… CONTINUE READING