Post‐poliomyelitis syndrome

@article{Trojan2005PostpoliomyelitisS,
  title={Post‐poliomyelitis syndrome},
  author={Daria A. Trojan and Neil R. Cashman},
  journal={Muscle \& Nerve},
  year={2005},
  volume={31}
}
Post‐poliomyelitis syndrome (PPS) is a common neurological disorder that occurs in a large proportion of individuals who have recovered from paralytic poliomyelitis. The main clinical features are new weakness, muscular fatigability, general fatigue, and pain. The primary criteria necessary for the diagnosis of PPS are a history of paralytic poliomyelitis, partial or complete recovery of neurological function followed by a period of stability (usually several decades), persistent new muscle… Expand
[Post-polio syndrome].
Post-polio syndrome (PPS) is characterized by new muscular weakness, atrophy, general and muscular fatigue, decreased endurance, pain, and loss of function several years after acute polio. BetweenExpand
Post-poliomyelitis syndrome as a possible viral disease.
TLDR
This review summarized current concepts on post-polio syndrome (PPS), a condition that may arise in polio survivors after partial or complete functional recovery followed by a prolonged interval of stable neurological function, and the possible pathogenic role of persistent poliovirus infection and chronic inflammation. Expand
Post-poliomyelitis syndrome: case report.
TLDR
The case of PPS is reported in a patient, 40 years, that thirty-five years after had had paralytic poliomyelitis, developed new symptoms of fatigue, muscular atrophy, dyspnea, difficulties in deambulation and muscular and joint pain. Expand
[Post-polio syndrome. Part I. The "legacy" of forgotten disease, challenges for professionals and polio survivors].
  • E. Matyja
  • Medicine
  • Neurologia i neurochirurgia polska
  • 2012
TLDR
It is established that polio has an additional, slowly progressive phase, called post-polio syndrome (PPS) that develops 30-40 years after the acute poliomyelitis in 25-80% of paralytic and about 40% of nonparalytic polio survivors. Expand
Post-polio Syndrome: More Than Just a Lower Motor Neuron Disease
TLDR
No validated diagnostic, monitoring, or prognostic markers have been developed in PPS to date and the mainstay of therapy centers on symptomatic relief and individualized rehabilitation strategies such as energy conservation and muscle strengthening exercise regimes. Expand
A fatal neuromuscular disease in an adult patient after poliomyelitis in early childhood: Consideration of the pathology of post‐polio syndrome
TLDR
The features in this case may have represented the pathology of long‐standing and/or fatal PPS itself, and not ALS, thus raising doubt as to the clinical diagnosis of amyotrophic lateral sclerosis (ALS) following PPS. Expand
POST-POLIO SYNDROME REPORT OF TWO CASES
TLDR
This article seeks to question the concept of polio as a static disease, since it is a process difficult to diagnose and treat, as in both cases presented here. Expand
Post-polio syndrome: clinical manifestations and cerebrospinal fluid markers
TLDR
In the light of recent studies demonstrating a partial beneficial effect of intravenous immunoglobulin, this article will focus on cerebrospinal fluid biomarkers reflecting disease activity and pathogenic processes in PPS. Expand
Aging and sequelae of poliomyelitis.
TLDR
The therapeutic care of this late functional deterioration requires regular monitoring check-ups in order to implement preventive measures and appropriate treatment. Expand
Mise au point Aging and sequelae of poliomyelitis
Objective. – We estimate that there are about 50,000 persons who survived poliomyelitis in their childhood in France (mean age estimated between 50 and 65 years). After a few decades of stability, 30Expand
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TLDR
The epidemiology, pathophysiology, characteristics, assessment, and rehabilitation care of the patient with post-polio syndrome are reviewed. Expand
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TLDR
The PPS is now a well-recognized entity encompassing the late manifestations that occur because of previous poliomyelitis, and treatment is primarily supportive, although nonfatiguing strengthening exercise may improve strength over the short term. Expand
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TLDR
There is no specific diagnostic test for post-poliomyelitis syndrome, which continues to be a diagnosis of exclusion in an individual with symptoms and signs of the disorder. Expand
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TLDR
A better understanding of PPS and PPMA will allow more effective management of these patients' problems and might also provide insight into other motor neuron and neuromuscular junction diseases. Expand
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TLDR
The findings suggest that the degree of initial motor unit involvement as measured by weakness at acute polio, and possibly the aging process and overuse are important in predicting PPS. Expand
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TLDR
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TLDR
Exercise may be helpful for many postpolio patients, but the prescription must be tailored to the individual to avoid problems of overuse or excessive fatigue. Expand
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TLDR
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TLDR
It is concluded that the extensive reinnervation of denervated muscle that occurs in paralytic poliomyelitis may be followed by late denervation of the previously reinnervate muscle fibers. Expand
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TLDR
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