Post‐mortem analysis for two prevalent β‐oxidation mutations in sudden infant death

@article{Yang2007PostmortemAF,
  title={Post‐mortem analysis for two prevalent $\beta$‐oxidation mutations in sudden infant death},
  author={Zi Yang and Patrick E. Lantz and Jamal A. Ibdah},
  journal={Pediatrics International},
  year={2007},
  volume={49}
}
Background: Fatty acid oxidation disorders may cause sudden and unexpected infant death and are associated with the histological hallmark of hepatic steatosis. The goal of the present study was to assess the value of post‐mortem molecular analysis for medium‐chain acyl‐coenzyme A dehydrogenase (MCAD) and mitochondrial trifunctional protein (MTP) defects in unexplained sudden infant death (SID) associated with fatty infiltration of the liver. MCAD catalyzes the first step of medium‐chain fatty… 
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