Post‐Translational Processing of Procollagens

@article{Kivirikko1985PostTranslationalPO,
  title={Post‐Translational Processing of Procollagens},
  author={Kari I. Kivirikko and Raili Myllylä},
  journal={Annals of the New York Academy of Sciences},
  year={1985},
  volume={460}
}
Collagen biosynthesis is characterized by the presence of an unusually large number of cotranslational and post-translational modifications, many of which are unique to collagens and a few other proteins with collagen-like amino acid sequences. The posttranslational processing of procollagens can be regarded as occurring in two stages (FIGURE 1). Intracellular modifications, together with synthesis of the polypeptide chains, result in the formation of triple-helical procollagen molecules, and… Expand

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