Possible roles of retrograde messengers on LTP, LTD, and associative memory.

@article{Migliore1997PossibleRO,
  title={Possible roles of retrograde messengers on LTP, LTD, and associative memory.},
  author={Michele Migliore and F. Alicata and G. F. Ayala},
  journal={Bio Systems},
  year={1997},
  volume={40 1-2},
  pages={127-32}
}
There are still no clear biophysical models for Associative Long-Term Potentiation (LTP) and Depression (LTD) in the hippocampus, where two populations of synapses targeted to the same receptive field are involved. Here we propose a model that allows an interpretation of the experiments in terms of the molecular processes that may be involved in associative memory. The model suggests that retrograde messengers could have a critical role in the induction and maintenance of associative LTP and… CONTINUE READING