Possible roles of CTGF/Hcs24 in the initiation and development of ossification of the posterior longitudinal ligament.

@article{Yamamoto2002PossibleRO,
  title={Possible roles of CTGF/Hcs24 in the initiation and development of ossification of the posterior longitudinal ligament.},
  author={Yuji Yamamoto and Ken-ichi Furukawa and Kazumasa Ueyama and Tohru Nakanishi and Masaharu Takigawa and Seiko Harata},
  journal={Spine},
  year={2002},
  volume={27 17},
  pages={1852-7}
}
STUDY DESIGN A biochemical and histochemical study investigating the role of CTGF/Hcs24 in the ossification of the posterior longitudinal ligament (OPLL) was conducted. OBJECTIVE To clarify the involvement of CTGF/Hcs24 in ectopic bone formation in OPLL through endochondral ossification using human tissue. SUMMARY OF BACKGROUND DATA Previous studies have shown that various cytokines are involved in the occurrence or development of ectopic bone formation in OPLL. Recently, the authors cloned… CONTINUE READING
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