Possible role of nitric oxide on fertile and asthenozoospermic infertile human sperm functions.

@article{Zhang1996PossibleRO,
  title={Possible role of nitric oxide on fertile and asthenozoospermic infertile human sperm functions.},
  author={Hua-bin Zhang and Ri Liang Zheng},
  journal={Free radical research},
  year={1996},
  volume={25 4},
  pages={347-54}
}
The capacity of human sperm fertilization is principally dependent on sperm motility and membrane integrity. Oxygen-derived free radicals, such as superoxide anion, are known to impair sperm motility and membrane integrity by inducing membrane lipid peroxidation (LPO). Nitric oxide (NO), a biologically active free radical, has recently been shown to inactivate superoxide and increase intracellular guanosine-3', 5'-cyclic monophosphate (cGMP). The aim of this study is to investigate the effects… CONTINUE READING

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