Possible role of DNA hypomethylation in the induction of SLE: relationship to the transcription of human endogenous retroviruses.

Abstract

OBJECTIVE We investigated the contribution of DNA methyltransferase activity to the transcription of human endogenous retroviruses (HERV), which have been reported to be a plausible causative agent for systemic lupus erythematosus (SLE). METHODS The reverse transcriptase-polymerase chain reaction (RT-PCR) and real-time quantitative-PCR (RQ-PCR) were used… (More)

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Cite this paper

@article{Ogasawara2003PossibleRO, title={Possible role of DNA hypomethylation in the induction of SLE: relationship to the transcription of human endogenous retroviruses.}, author={H. Ogasawara and M. Okada and Hitomi Kaneko and Toshimitsu Hishikawa and Iwao Sekigawa and H. Hashimoto}, journal={Clinical and experimental rheumatology}, year={2003}, volume={21 6}, pages={733-8} }