Possible role for salivary gland protein in taste reception indicated by homology to lipophilic-ligand carrier proteins

@article{Schmale1990PossibleRF,
  title={Possible role for salivary gland protein in taste reception indicated by homology to lipophilic-ligand carrier proteins},
  author={Hartwig Schmale and Heidi Holtgreve-Grez and Heidje Christiansen},
  journal={Nature},
  year={1990},
  volume={343},
  pages={366-369}
}
SENSORY transduction in taste and olfaction, the principal chemical senses, seems to be mediated by membrane-associated proteins on the apical surfaces of the respective receptor cells1,2. The recent isolation and characterization of soluble 'odorant-binding proteins9 secreted from the nasal glands of rat3, cow4and frog5, led to the hypothesis that these proteins function as necessary cofactors in olfactory transduction by concentrating and delivering odorants to the receptors6. The primary… CONTINUE READING