Possible peptide chain termination mutants in thymide kinase gene of a mammalian virus, herpes simplex virus.

@article{Summers1975PossiblePC,
  title={Possible peptide chain termination mutants in thymide kinase gene of a mammalian virus, herpes simplex virus.},
  author={William K Summers and Michael J. M. Wagner and William C. Summers},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1975},
  volume={72 10},
  pages={4081-4}
}
Mutations in the viral gene coding for the thymidine kinase (ATP:thymidine 5'-phosphotransferase, EC 2.7.1.75) induced by herpes simplex virus have been obtained by selection of virus resistant to bromodeoxyuridine when grown in thymidine-kinase-deficient LMTK- mouse cells. Proteins labeled after infection of Vero (monkey) cells with herpes simplex virus… CONTINUE READING