Possible participation of outer mitochondrial membrane cytonchrome B5 in steroidogenesis in zona glomerulosa of rat adrenal cortex.

@article{Mitani2004PossiblePO,
  title={Possible participation of outer mitochondrial membrane cytonchrome B5 in steroidogenesis in zona glomerulosa of rat adrenal cortex.},
  author={Fumiko Mitani and Tadashi Ogishima and Kuniaki Mukai and Ryota Hoshino and Kenichi Watanabe and Makoto Suematsu},
  journal={Endocrine research},
  year={2004},
  volume={30 4},
  pages={
          639-44
        }
}
Outer mitochondrial membrane cytochrome b5 (OMb) originally found in rat liver is an isoform of cytochrome b5 (b5) of the endoplasmic reticulum. In contrast to accumulated data on the physiological roles of b5, functions of OMb have not been well characterized except for its involvement in regeneration of ascorbic acid [i.e., in a semidehydroascorbate reductase (SDAR) system]. By using highly specific antibodies against rat OMb, we found immunohistochemically that OMb in the rat adrenal gland… CONTINUE READING
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