Possible new role for NF-kappaB in the resolution of inflammation.

@article{Lawrence2001PossibleNR,
  title={Possible new role for NF-kappaB in the resolution of inflammation.},
  author={T Lawrence and Derek W Gilroy and Paul Richard Colville-Nash and Derek Albert Willoughby},
  journal={Nature medicine},
  year={2001},
  volume={7 12},
  pages={
          1291-7
        }
}
Inflammation involves the sequential activation of signaling pathways leading to the production of both pro- and anti-inflammatory mediators. Although much attention has focused on pro-inflammatory pathways that initiate inflammation, relatively little is known about the mechanisms that switch off inflammation and resolve the inflammatory response. The transcription factor NF-kappaB is thought to have a central role in the induction of pro-inflammatory gene expression and has attracted interest… CONTINUE READING

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