Possible modulating actions of plant extracts on the chromosome breaking activity of MMC and Ara-C in human lymphocytes in vitro.

@article{Roncada2004PossibleMA,
  title={Possible modulating actions of plant extracts on the chromosome breaking activity of MMC and Ara-C in human lymphocytes in vitro.},
  author={T Roncada and Veronica Elisa Pimenta Vicentini and M{\'a}rio S{\'e}rgio Mantovani},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2004},
  volume={18 5},
  pages={617-22}
}
Plants popularly used as medicine have been seen as promising natural agents by the pharmaceutical industry. In the present study the action of Psidium guajava L. (Pg) and Achillea millefolium L. (Am) infusions on chromosomal aberration formation in human lymphocyte system in vitro was assessed, associating them with the alkylating agent mitomycin C (MMC) and the DNA repair inhibitor cytosine-beta-arabin-furanoside (Ara-C). The cells were cultivated for 72 h and treated continuously with Pg and… CONTINUE READING