Possible mechanisms for changes in renal hemodynamics during pregnancy: studies from animal models.

@article{Conrad1987PossibleMF,
  title={Possible mechanisms for changes in renal hemodynamics during pregnancy: studies from animal models.},
  author={Kirk P. Conrad},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={1987},
  volume={9 4},
  pages={253-9}
}
  • Kirk P. Conrad
  • Published 1987 in
    American journal of kidney diseases : the…
Glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) increase during gestation in humans, rats, rabbits, dogs, and sheep. Serial studies performed in chronically instrumented conscious pregnant rats show that the relative time course of changes in renal hemodynamics resembles that of human pregnancy. Because gestational alterations of renal hemodynamics in humans are similar to those in other mammalian species, animal models are being used to investigate possible mechanisms… CONTINUE READING
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