Possible mechanism of chrysotile asbestos-stimulated superoxide anion production in guinea pig alveolar macrophages.

Abstract

Excessive production of active oxygen radicals by macrophages is proposed to play an important role in asbestos-related diseases. The purpose of this study was to examine the capacity and mechanisms of action of various forms of asbestos to stimulate superoxide anion production by guinea pig alveolar macrophages. Chrysotile, but not the amphiboles… (More)

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