Possible mechanism by which stress accelerates growth of virally derived tumors.

@article{Romero1992PossibleMB,
  title={Possible mechanism by which stress accelerates growth of virally derived tumors.},
  author={Lina M Romero and Kathleen M. Raley-Susman and David Redish and Sheila M. Brooke and H C Horner and Robert Morris Sapolsky},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 22},
  pages={11084-7}
}
Stress accelerates the growth of certain types of tumors. Here we report a possible metabolic mechanism underlying this phenomenon. Some early features of transformation include increased number of glucose transporters and greatly enhanced rates of glucose uptake; this adaptation accommodates the vast energy demands needed for neoplastic growth. In contrast, glucocorticoids, a class of steroid hormones secreted during stress, inhibit glucose transport in various tissues; this is one route by… CONTINUE READING

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