Possible mechanism by which renal sympathetic denervation improves left ventricular remodelling after myocardial infarction.

Abstract

NEW FINDINGS What is the central question of this study? The enzyme system that is responsible for extracellular matrix (ECM) turnover is the matrix metalloproteinases (MMPs), which can be blocked by the tissue inhibitors of MMPs (TIMPs). Whether renal sympathetic denervation (RSD) is able to ameliorate post-myocardial infarction left ventricular… (More)
DOI: 10.1113/EP085302

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