Possible involvement of protein kinase C in the maintenance of hypertension in spontaneously hypertensive rats.

@article{Murakawa1988PossibleIO,
  title={Possible involvement of protein kinase C in the maintenance of hypertension in spontaneously hypertensive rats.},
  author={Kazushige Murakawa and Masashi Kohno and Kenichi Yasunari and Koji Yokokawa and Takeshi Horio and Tadanao Takeda},
  journal={Journal of hypertension. Supplement : official journal of the International Society of Hypertension},
  year={1988},
  volume={6 4},
  pages={S157-9}
}
Calcium-activated phospholipid-dependent protein kinase (protein kinase C) and cyclic AMP-dependent protein kinase (protein kinase A) were measured in tissue extracts of aortas from 7-, 14- and 20-week-old spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Protein kinase C and protein kinase A activity was significantly higher in 14- and 20… CONTINUE READING