Possible involvement of nitric oxide in arginine-induced analgesia.

  • X Q Ji, X. Zu Zhu
  • Published 1993 in
    Zhongguo yao li xue bao = Acta pharmacologica…

Abstract

Intracerebroventricular injection (icv) of 1-arginine (Arg, 0.5, 5.0, 50 micrograms) produced a dose-dependent prolongation in the hot-plate latency in mice. A similar result was obtained when nitroprusside (0.1, 1.0, 10 micrograms, icv) was given. Naloxone (2 mg.kg-1, ip) failed to antagonize the effects of Arg or nitroprusside. But Arg-induced… (More)

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Cite this paper

@article{Ji1993PossibleIO, title={Possible involvement of nitric oxide in arginine-induced analgesia.}, author={X Q Ji and X. Zu Zhu}, journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica}, year={1993}, volume={14 4}, pages={289-91} }