Possible involvement of amine oxidase inhibition in the sympathetic activation induced by khat (Catha edulis) chewing in humans.

@article{Nencini1984PossibleIO,
  title={Possible involvement of amine oxidase inhibition in the sympathetic activation induced by khat (Catha edulis) chewing in humans.},
  author={P. Nencini and Gino Amiconi and Olivia Befani and M A Abdullahi and Maria Cristina Anania},
  journal={Journal of ethnopharmacology},
  year={1984},
  volume={11 1},
  pages={79-86}
}
The possibility that phenylalkylamines (cathinone and cathine) of khat, like amphetamines, are amine oxidase inhibitors with clinical significance is evaluated. Results show that khat chewing induces a significant increase in blood pressure, body temperature and urinary catecholamines in khat naive subjects. On the other hand, in habitual consumers a significant enhancement only of blood pressure is observed. Urinary concentrations of vanilmandelic acid show an inhibitory trend in both groups… CONTINUE READING