Possible interrelationship between gluconeogenesis and ketogenesis in the liver

@article{Kmmel1983PossibleIB,
  title={Possible interrelationship between gluconeogenesis and ketogenesis in the liver},
  author={L. K{\"u}mmel},
  journal={Bioscience Reports},
  year={1983},
  volume={3},
  pages={643-646}
}
  • L. Kümmel
  • Published 1983
  • Chemistry, Medicine
  • Bioscience Reports
Effeects of various ketogenic substrates on gluconeogenesis from lactate were examined. D,L-3-Hydroxybutyrate (5 mM) stimulated gluconeogenesis by 41%, the effect being the same as that of 5 mM acetate (49%). No stimulating effect of acetoacetate was observed; conversely, acetoacetate (up to 40 mM) partially or completely abolished the observed stimulating effects of acetate, oleate, and 3-hydroxybutyrate. The results suggest that, in intact liver cells, pyruvate is transported into… Expand
Mitochondrial pyruvate carrier—A possible link between gluconeogenesis and ketogenesis in the liver
  • L. Kümmel
  • Chemistry, Medicine
  • Bioscience reports
  • 1987
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