Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan

@article{Wang2007PossibleIB,
  title={Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan},
  author={Tso-Jen Wang and San-Yuan Huang and Wei-Wen Lin and Hsin-Yi Lo and Pei-Lin Wu and Yu-Shan Wang and Yi-Syuan Wu and Huei-Chen Ko and Jean C. Shih and Ru-Band Lu},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2007},
  volume={31},
  pages={108-114}
}

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  • Psychology, Medicine
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
  • 2008
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References

SHOWING 1-10 OF 73 REFERENCES

Association of 5-HT1B receptor gene and antisocial behavior in alcoholism

Based on the examination of 164 alcoholic subjects, an association was found between a lower frequency of the 5-HT 1B 861C allele, antisocial personality traits and conduct disorder in alcohol-dependent subjects.

Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males.

Neither antisocial alcoholism nor antisocial personality disorder was associated with the genetic variants of MAO-A gene, either individually or for the haplotype, or for antissocial personality disorder without alcoholism.

No association between DRD2 locus and alcoholism after controlling the ADH and ALDH genotypes in Chinese Han population.

No significant association exists between the genetic variants at the DRD2 locus and alcoholism in the Chinese Han population, and several different stratifications by ADH and ALDH2 genotypes were examined.

Different allele distribution of a regulatory MAOA gene promoter polymorphism in antisocial and anxious-depressive alcoholics

It is suggested that the 3-repeat allele of the MAOA polymorphism contributes modestly to the dimension of over- and underreactive behaviors as possible antecedents of alcoholism.

The TaqI A1 allele of the dopamine D2 receptor gene and alcoholism in Brazil: association and interaction with stress and harm avoidance on severity prediction.

The DRD2 TaqI A1 allele showed significant interaction with stress and harm avoidance in predicting the severity of physiologic dependence, and with harm avoidance for the number of antisocial personality symptoms.

Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism.

It is concluded that the functional and structural variations in DRD2 gene do not play a major role in the development of alcoholism subtypes in a sample of alcoholics and normal controls.
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