Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan

@article{Wang2007PossibleIB,
  title={Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan},
  author={Tso-Jen Wang and San-Yuan Huang and Wei-Wen Lin and Hsin-Yi Lo and Pei-Lin Wu and Yu-Shan Wang and Yi-Syuan Wu and Huei-Chen Ko and Jean C. Shih and Ru-Band Lu},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2007},
  volume={31},
  pages={108-114}
}
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34 Citations
Highly Influential Citations
2
Background Citations
15
Methods Citations
3
Results Citations
4

34 Citations

MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder.

The possible interaction of MAOA and AL DH2 gene is associated with Antisocial ALC in Han Chinese males in Taiwan, however, the protective effects of the ALDH2*2 allele against alcoholism might disappear in subjects with ASPD and carrying MAOA-uVNTR 4-repeat allele in the Han Chinese male population.

Association study of DRD2 and MAOA genes with subtyped alcoholism comorbid with bipolar disorder in Han Chinese

Interaction between Serotonin Transporter and Serotonin Receptor 1 B genes polymorphisms may be associated with antisocial alcoholism

This study suggests that neither the 5-HTTLPR gene nor the5-HT1B G861C polymorphism alone is a risk factor for antisocial alcoholism in Taiwan’s Han Chinese population, but that the interaction between both genes may increase susceptibility to antissocial alcoholism.

The association between DRD2/ANKK1, 5‐HTTLPR gene, and specific personality trait on antisocial alcoholism among Han Chinese in Taiwan

  • Chin-Yeh WuYi-Syuan Wu R. Lu
  • Psychology, Medicine
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
  • 2008
Recruitment of antisocial non‐alcoholics from the Han Chinese population in Taiwan served as an important control group in examining Cloninger's hypothesis that type II alcoholism was associated with higher novelty seeking and less harm avoidance behaviors.

The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence.

This study suggests that the 5HT1B gene A-161T polymorphism alone is not a risk factor for increasing susceptibility to either AD or its subtypes, however, 5 HT1B genes might be one of the common genetic factors between the ANX/DEP ALC and antisocial ALC subgroups.

Specific personality traits and dopamine, serotonin genes in anxiety–depressive alcoholism among Han Chinese in Taiwan

MAOA interacts with the ALDH2 gene in anxiety-depression alcohol dependence.

It is concluded that the MAOA and ALDH2 genes interact in ANX/DEP ALC.

Interaction between ALDH2*1*1 and DRD2/ANKK1 TaqI A1A1 genes may be associated with antisocial personality disorder not co‐morbid with alcoholism

The results suggest that the DRD2/ANKK1 and ALDH2 genes interacted in the antisocial non‐ALC group; a connection neglected in previous studies caused by not separating antisocial ALC from ASPD.

The association between the SLC6A3 VNTR 9-repeat allele and alcoholism-a meta-analysis.

Meta-analyses suggest a possible association between the SLC6A3 VNTR A9 and alcoholic subgroup with AWS or DT, and a total of 13 research articles were included in the meta-an analyses.

Association study of the SLC6A3 VNTR (DAT) and DRD2/ANKK1 Taq1A polymorphisms with alcohol dependence in a population from northeastern Brazil.

Findings suggest that A9 allele and A9/A9 genotype of the SLC6A3 40 bp-VNTR are involved in the vulnerability to AD in the population studied, but for the DRD2/ANKK1 SNP does not present contributions to the development of AD.

References

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