Possible enhancement of the cardiotoxicity of doxorubicin when combined with mitomycin C.

@article{Villani1985PossibleEO,
  title={Possible enhancement of the cardiotoxicity of doxorubicin when combined with mitomycin C.},
  author={Fabrizio Villani and R Comazzi and G Lacaita and A. Guindani and V Genitoni and Alberto Volonterio and M. Brambilla},
  journal={Medical oncology and tumor pharmacotherapy},
  year={1985},
  volume={2 2},
  pages={93-7}
}
Forty-six patients with recurrent metastatic breast cancer were treated with a combination chemotherapy including doxorubicin and mitomycin C. Myocardial contractility was monitored by means of echocardiography. During therapy there was a progressive deterioration of myocardial function, and this phenomenon was found to be linearly correlated to the… CONTINUE READING