Possible differences in the two Z chromosomes in male chickens and evolution of MHM sequences in Galliformes

@article{Itoh2011PossibleDI,
  title={Possible differences in the two Z chromosomes in male chickens and evolution of MHM sequences in Galliformes},
  author={Yuichiro Itoh and Kathy Kampf and Arthur P Arnold},
  journal={Chromosoma},
  year={2011},
  volume={120},
  pages={587-598}
}
The male hypermethylated (MHM) region of the chicken Z chromosome encodes a non-coding RNA that is expressed only in females. The MHM sequence is found only in galliform birds, and Z genes near this region show an unusual degree of dosage compensation between males and females despite the overall low level of dosage compensation in Z chromosome gene expression in birds. Here we report that the MHM locus shows a dramatic sex difference in the configuration of chromatin, open in females and… CONTINUE READING
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