Possible coordinated gene expressions for FGF receptor, FGF-5, and FGF-2 following seizures.

@article{GmezPinilla1995PossibleCG,
  title={Possible coordinated gene expressions for FGF receptor, FGF-5, and FGF-2 following seizures.},
  author={Fernando G{\'o}mez-Pinilla and Erna van der Wal and Carl Cotman},
  journal={Experimental neurology},
  year={1995},
  volume={133 2},
  pages={164-74}
}
We have examined the influence of afferent activity that may trigger a coordinated response between ligands and their signal transduction receptors, as part of the regulation of the fibroblast growth factor (FGF) system. Epileptiform activity was induced by kainic acid injection, and in situ hybridization was used to assess the progress of changes in distribution and intensities of FGF receptor 1 (FGFR-1), FGF-5, and FGF-2 mRNAs. Our results showed that at early stages (3 h) afferent activity… CONTINUE READING