Possible contribution of circulating interleukin-10 (IL-10) to anti-tumor immunity and prognosis in patients with unresectable hepatocellular carcinoma.

@article{Hattori2003PossibleCO,
  title={Possible contribution of circulating interleukin-10 (IL-10) to anti-tumor immunity and prognosis in patients with unresectable hepatocellular carcinoma.},
  author={Etsuko Hattori and Kazuo Okumoto and Tohru Adachi and Tadashi Takeda and Jun itsu Ito and Kazuhiko Sugahara and Hisayoshi Fujitsu Limited Watanabe and Koji Saito and Takafumi Saito and Hitoshi Togashi and Sumio Kawata},
  journal={Hepatology research : the official journal of the Japan Society of Hepatology},
  year={2003},
  volume={27 4},
  pages={
          309-314
        }
}
OBJECTIVES: Interleukin-10 (IL-10) has been implicated in immune deficiency in patients with cancer. The relationship of this cytokine as measured in serum to anti-tumor immunity and prognosis was investigated in unresectable hepatocellular carcinoma. METHODS: This study consisted of 74 consecutive patients with unresectable hepatocellular carcinoma (median age, 65 years). Forty-four healthy age-matched subjects and 32 patients with cirrhosis but no carcinoma served as controls. Patients with… CONTINUE READING
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