Possible cases of sexual and congenital transmission of sleeping sickness

  title={Possible cases of sexual and congenital transmission of sleeping sickness},
  author={G. Rocha and Andr{\'e}a Martins and Gustavo Falc{\~a}o Gama and F. Brand{\~a}o and Jorge Atouguia},
  journal={The Lancet},
Congenital Trypanosomiasis in an 11-Year-Old Girl at the Brazzaville University Hospital
A case of Human African Trypanosomiasis is reported in an 11-year-old girl who has never been to an endemic area and who has no other risk exposure factor apart from the fact she was born from mother who was affected by the disease and treated for 10 years during pregnancy.
The Unknown Risk of Vertical Transmission in Sleeping Sickness—A Literature Review
This review systematically summarizes the literature on the vertical transmission of HAT, to the knowledge for the first time, and concludes that awareness of congenital HAT is insufficient, and as a result opportunities for an early diagnosis in newborns may be missed.
Vertical transmission of human African trypanosomiasis: Clinical evolution and brain MRI of a mother and her son
A 22-year-old female referred to the authors' hospital from another in May 2013 to investigate a probable leukodystrophy showed slowing of ideomotor function, general hypotonia, clonic limb movements, and increased deep tendon reflexes, with global brain atrophy for her age.
Role of Serodiagnosis of Human African Trypanosomiasis (Sleeping Sickness)
Human  African  trypanosomiasis  (HAT) or  sleeping  sickness,  is  caused  by  Trypanosoma  brucei  gambiense,  which  is  a  chronic form of the disease present in western and central Africa and
Transfusion‐transmitted American and African trypanosomiasis (Chagas disease and sleeping sickness): neglected or reality?
The systematic classification about these two protozoa is shown, and it is shown that they all have in common some peculiarities; these features are put together in Table 2.
Human African trypanosomiasis: a review of non-endemic cases in the past 20 years.
African Sleeping Sickness
All aspects of HAT are exposed, emphasizing historical milestones and scientific background, and diagnosis still relies on direct microscopic trypanosome detection or after concentration techniques.
Trypanosoma brucei gambiense Infections in Mice Lead to Tropism to the Reproductive Organs, and Horizontal and Vertical Transmission
Trypanosoma brucei gambiense, transmitted by the tsetse fly, is the main causative agent of Human African trypanosomosis in West Africa and poses a significant health risk to 70 million people.
Latent Trypanosoma brucei gambiense foci in Uganda: a silent epidemic in children and adults?
Observations suggest the possibility of a silent focus of disease, where all infected individuals are in a latent stage, and highlight the limited understanding of the local natural history and disease progression of T. b.


[Use of molecular biology in the diagnosis of human African trypanosomiasis].
Within the framework of active screening, PCR carried out on blood samples prior to serological tests could be helpful in identifying suspected infection and for application on cerebrospinal fluid samples, PCR achieves better sensitivity than conventional techniques and thus can contribute to staging of the disease.
[Interpretation of the CATT (Card Agglutination Trypanosomiasis Test) in the screening for human trypanosomiasis due to Trypanosoma brucei gambiense].
The existence of patients whose gland punction was proved positive whereas the total blood CATT remained negative, has led the authors to make a survey with the CATT in parallel (on blood and serum CATT) on a 2,030 subjects sample in the Boko Songho site (Congo-Bouenza area).