Possible association of the CD4 gene polymorphism with vitiligo in an Iranian population

@article{Zamani2010PossibleAO,
  title={Possible association of the CD4 gene polymorphism with vitiligo in an Iranian population},
  author={Mahdi Zamani and Mohammad Amin Tabatabaiefar and Solmaz Mosayyebi and Alireza Mashaghi and Parvin Mansouri},
  journal={Clinical and Experimental Dermatology},
  year={2010},
  volume={35}
}
Background.  Vitiligo is an acquired idiopathic and polygenic disorder with progressive depigmentation of circumscribed patches. Its exact pathogenesis is unknown. The CD4 gene plays an important role in the cell‐mediated immune response and its association with type 1 diabetes mellitus, which is an autoimmune disease, has been previously reported. 
Immunopathogenesis of vitiligo.
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Contribution of HLA class II genes, DRB4*01:01, DRB1*07:01, and DQB1*03:03:2 to clinical features of Vitiligo disease in Iranian population.
TLDR
The findings on different subtypes of Vitiligo suggest that, despite a more apparent autoimmune involvement, a non-autoimmune nature for the etiology of VitILigo should also be considered.
Association of CD4 SNPs with fat percentage of Holstein cattle.
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