Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample.

@article{Georgi2007PossibleAB,
  title={Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample.},
  author={Alexander Georgi and Rami Abou Jamra and Katrin Klein and Angela Wolf Villela and Johannes Schumacher and Tim E. E. Becker and Torsten Paul and Christine Schmael and Susanne Hoefels and Norman Klopp and Thomas Illig and P. Propping and Sven Cichon and Markus M. N{\"o}then and Thomas G. Schulze and Marcella Rietschel},
  journal={Psychiatric genetics},
  year={2007},
  volume={17 5},
  pages={
          308-10
        }
}
  • Alexander Georgi, Rami Abou Jamra, +13 authors Marcella Rietschel
  • Published in Psychiatric genetics 2007
  • Psychology, Medicine
  • Genetic variation in glutamatergic signalling pathways is believed to play a substantial role in the aetiology of schizophrenia. The N-methyl-D-aspartate receptor subunit gene GRIN1 has been proposed as a candidate gene for schizophrenia. We tested for a potential association between schizophrenia and four single nucleotide polymorphisms (rs4880213, rs11146020, rs6293, and rs10747050) and one microsatellite marker at GRIN1 in a German sample of 354 patients and 323 controls. We found… CONTINUE READING

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