Possible association between HPV16 E7 protein level and cytokeratin 19.

  title={Possible association between HPV16 E7 protein level and cytokeratin 19.},
  author={Gianfranco Favia and Darja Kanduc and Lorenzo Lo Muzio and Alberta Lucchese and Rosario Serpico},
  journal={International journal of cancer},
  volume={111 5},
The mechanisms employed by human papillomaviruses (HPVs) to control the replication of the viral genome and the expression of the viral genes are extremely complex and further complicated by the fact that the viral life cycle is intricately tied to the differentiation program of its host epithelial tissue. Indeed, HPV-induced immortalization of keratinocytes and disruption of the normal cytokeratin (CK) expression pattern progress pari passu during the stepwise process that preludes to squamous… CONTINUE READING

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