Corpus ID: 80803595

Possible Role of Brain-Derived Neurotrophic Factor in the Pathogenesis of Coronary Artery Disease

@article{JunyaEjiri2005PossibleRO,
  title={Possible Role of Brain-Derived Neurotrophic Factor in the Pathogenesis of Coronary Artery Disease},
  author={JunyaEjiri and NobutakaInoue and SeiichiKobayashi and RioShiraki and KazunoriOtsui and TomoyukiHonjo and MotonoriTakahashi and YoshitakaOhashi and ShinobuIchikawa and MitsuyasuTerashima and TakaoMori and KojiroAwano and ToshiroShinke and JunyaShite and Ken-ichiHirata and HiroshiYokozaki and SeinosukeKawashima and MitsuhiroYokoyama},
  journal={Circulation},
  year={2005}
}
Background— The neurotrophin (NT) family, including nerve growth factor NT-3 and brain-derived neurotrophic factor (BDNF), has a critical role in the survival, growth, maintenance, and death of central and peripheral neurons. NTs and their receptors are expressed in atherosclerotic lesions; however, their significance in cardiovascular disease remains unclear. Methods and Results— To clarify the role of NTs in the pathogenesis of coronary artery disease, NT plasma levels in the aorta, coronary… Expand
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