Possible Role of Basidiospores as Air-borne Allergens

  title={Possible Role of Basidiospores as Air-borne Allergens},
  author={Philip Herries Gregory and J. M. Hirst},
THE role of air-borne mould spores in asthma, especially Alternaria and Cladosporium, has been recognized as the result of the work of Feinberg1 and Durham2. These workers used mainly the gravity slide and Petri dish exposure method to determine the spore content of the air. Both methods are highly selective for different reasons : the former catches larger pollen grains and spores and rarely catches small spores, while the latter only records organisms able to grow on the culture media exposed… 

Studies on airborne basidiospores

Field studies conducted in conjunction with air sampling have shown that basidiomycete fruiting bodies were also most prevalent during the spring and fall, and spores from 18 genera were identified from the atmosphere with Coprinus and Garicus being the most abundant spores in the spring.

Identification and concentration of airborne basidiospores

The atmosphere in Tulsa, Oklahoma has been monitored for the presence of basidiospores using Burkard Volumetric Spore Traps and shows that they are a significant component of the Tulsa atmosphere during certain periods.

Basidiomycete allergens

This review will emphasize the more recent work on basidiomycete allergens, including the production of recombinant allergens.

Atmospheric pollen and spores in relation to allergy. I

The multitude of seeds produced by an Agaric or a Boletus is innumerable; yet not one in ten thousand answers the purpose of propagation.

Atmospheric pollen and fungal spores in Hamilton in 1972 estimated by the Hirst automatic volumetric spore trap.

The Hirst automatic volumetric spore trap has been used for the first time in Canada to identify the quantitative and seasonal incidence of these particles.

Human sensitization to Ganoderma antigen.


Although Calvatia species demonstrate a number of similarities, there are distinctive structural and allergenic properties that indicate that C. craniiformis and C. rubroflava are potentially important aeroallergens.

Ingestive and inhalative allergy to the mushroom Boletus edulis

The two patients with strong anaphylactic reactions demonstrate that Be may have great allergenic potential, and it is noteworthy that not only can Basidiomycetes cause airborne allergy but also that edible mushrooms from this class can cause inhalative and intestinal allergy.

Occupational asthma to spores of Pleurotus cornucopiae.

Investigation of the case of a young man who developed severe asthma a few months after starting work in a factory producing a single type of mushroom led to demonstration of specific IgE and IgG against spore extracts and to isolation of one discriminant antigen.

Fungal allergens

Recent significant progress in isolating and characterizing relevant fungal allergens is summarized in the present review, and some allergens from the genera Alternaria, Aspergillus, and Cladosporium are now thoroughly characterized and several other genera, including some basidiomycetes, have been purified.




Estimates of spore content of the air can be made, with higher efficiency than by previous traps, at different times of day and thus be more closely correlated with variations in weather.

The Cascade Impactor: An Instrument for Sampling Coarse Aerosols

A new instrument is described which will sample windborne and stationary aerosols such as natural fogs and clouds, fine sprays, insecticidal mists, coarse dusts, pollen and spores, etc. By means of