Possible Bat Origin of Severe Acute Respiratory Syndrome Coronavirus 2
@article{Lau2020PossibleBO, title={Possible Bat Origin of Severe Acute Respiratory Syndrome Coronavirus 2}, author={S. Lau and Hayes K H Luk and A. Wong and Kenneth S M Li and Longchao Zhu and Zirong He and J. Fung and T. Chan and K. Fung and P. Woo}, journal={Emerging Infectious Diseases}, year={2020}, volume={26}, pages={1542 - 1547} }
We showed that severe acute respiratory syndrome coronavirus 2 is probably a novel recombinant virus. Its genome is closest to that of severe acute respiratory syndrome–related coronaviruses from horseshoe bats, and its receptor-binding domain is closest to that of pangolin viruses. Its origin and direct ancestral viruses have not been identified.
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References
SHOWING 1-10 OF 27 REFERENCES
A pneumonia outbreak associated with a new coronavirus of probable bat origin
- Biology, Medicine
- Nature
- 2020
- 7,420
- PDF
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
- Medicine, Biology
- Nature Microbiology
- 2020
- 2,105
- PDF
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
- Biology, Medicine
- Nature
- 2013
- 896
- PDF
Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 2005
- 1,151
- PDF
Ecoepidemiology and Complete Genome Comparison of Different Strains of Severe Acute Respiratory Syndrome-Related Rhinolophus Bat Coronavirus in China Reveal Bats as a Reservoir for Acute, Self-Limiting Infection That Allows Recombination Events
- Biology, Medicine
- Journal of Virology
- 2010
- 197
- PDF
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- Medicine
- The Lancet
- 2020
- 16,397
- PDF
Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats
- Biology, Medicine
- Emerging Microbes & Infections
- 2018
- 143
- PDF
Molecular epidemiology, evolution and phylogeny of SARS coronavirus
- Biology, Medicine
- Infection, Genetics and Evolution
- 2019
- 123
Polyphyletic origin of MERS coronaviruses and isolation of a novel clade A strain from dromedary camels in the United Arab Emirates
- Biology, Medicine
- Emerging Microbes & Infections
- 2016
- 20
- PDF