Positron emission tomography in Creutzfeldt-Jakob disease.

  title={Positron emission tomography in Creutzfeldt-Jakob disease.},
  author={Vjera A. Holthoff and J Sandmann and Gunter Pawlik and R. K. Schroeder and W-D Heiss},
  journal={Archives of neurology},
  volume={47 9},
Regional cerebral glucose metabolism was studied in a 73-year-old woman with autopsy-confirmed Creutzfeldt-Jakob disease, using positron emission tomography of 2-(18F)fluorodeoxyglucose. Regional absolute values were analyzed in 14 partially overlapping slices. Clinically, the patient was in an advanced stage of disease when positron emission tomographic scans revealed severe, diffuse hypometabolism, and neuropathological findings showed diffuse spongiform changes throughout the brain, with… CONTINUE READING