Positron emission tomographic studies of dopa-responsive dystonia and early-onset idiopathic parkinsonism.

@article{Snow1993PositronET,
  title={Positron emission tomographic studies of dopa-responsive dystonia and early-onset idiopathic parkinsonism.},
  author={Barry J Snow and Torbjoern G. Nygaard and Hitoshi Takahashi and Donald B. Calne},
  journal={Annals of neurology},
  year={1993},
  volume={34 5},
  pages={733-8}
}
There are two major syndromes presenting in the early decades of life with dystonia and parkinsonism: dopa-responsive dystonia (DRD) and early-onset idiopathic parkinsonism (EOIP). DRD presents predominantly in childhood with prominent dystonia and lesser degrees of parkinsonism. EOIP presents before age 40 with parkinsonism (often with associated dystonia). Both disorders are exquisitely sensitive to levodopa, although the long-term prognosis in each appears to be different. Some have… CONTINUE READING

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