Positively charged termini of the L2 minor capsid protein are necessary for papillomavirus infection.

@article{Roden2001PositivelyCT,
  title={Positively charged termini of the L2 minor capsid protein are necessary for papillomavirus infection.},
  author={Richard B S Roden and Patricia M Day and B K Bronzo and William H. Yutzy and Yongping Yang and Douglas R Lowy and John T. Schiller},
  journal={Journal of virology},
  year={2001},
  volume={75 21},
  pages={
          10493-7
        }
}
Coexpression of bovine papillomavirus L1 with L2 mutants lacking either eight N-terminal or nine C-terminal amino acids that encode positively charged domains resulted in wild-type levels of viral genome encapsidation. Despite wild-type binding to the cell surface, the resulting virions were noninfectious. An L2 mutant encoding a scrambled version of the nine C-terminal residues restored infectivity, in contrast to an L2 mutant encoding a scrambled version of the N-terminal residues. 

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L2, the minor capsid protein of papillomavirus.

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Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic.

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