Positive selection and sequence rearrangements generate extensive polymorphism in the gamete recognition protein bindin.

@article{Metz1996PositiveSA,
  title={Positive selection and sequence rearrangements generate extensive polymorphism in the gamete recognition protein bindin.},
  author={Edu. Metz and Stephen R Palumbi},
  journal={Molecular biology and evolution},
  year={1996},
  volume={13 2},
  pages={397-406}
}
Bindin is a gamete recognition protein of sea urchins that mediates species-specific attachment of sperm to an egg-surface receptor during fertilization. Sequences of bindin from closely related urchins show fixed species-specific differences. Within species, highly polymorphic bindin alleles result from point substitution, insertion/deletion, and recombination. Since speciation, positive selection favoring allelic variants has generated diversity in bindin polypeptides. Intraspecific bindin… CONTINUE READING
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