Positive-end expiratory pressure reduces incidence of ventilator-associated pneumonia in nonhypoxemic patients*

@article{Manzano2008PositiveendEP,
  title={Positive-end expiratory pressure reduces incidence of ventilator-associated pneumonia in nonhypoxemic patients*},
  author={F. Manzano and E. Fern{\'a}ndez-Mond{\'e}jar and M. Colmenero and M. E. Poyatos and R. Rivera and J. Machado and I. Catal{\'a}n and A. Artigas},
  journal={Critical Care Medicine},
  year={2008},
  volume={36},
  pages={2225-2231}
}
Objective:To analyze the effect on clinical outcomes of prophylactic positive end expiratory pressure in nonhypoxemic ventilated patients. Design:Multicenter randomized controlled clinical trial. Setting:One trauma and two general intensive care units in two university hospitals. Patients:One hundred thirty-one mechanically ventilated patients with normal chest radiograph and Pao2/Fio2 above 250. Interventions:Patients were randomly allocated to receive mechanical ventilation with 5–8 cm H2O of… Expand
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