Positive end-expiratory pressure at minimal respiratory elastance represents the best compromise between mechanical stress and lung aeration in oleic acid induced lung injury

Abstract

INTRODUCTION Protective ventilatory strategies have been applied to prevent ventilator-induced lung injury in patients with acute lung injury (ALI). However, adjustment of positive end-expiratory pressure (PEEP) to avoid alveolar de-recruitment and hyperinflation remains difficult. An alternative is to set the PEEP based on minimizing respiratory system… (More)

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@article{Carvalho2007PositiveEP, title={Positive end-expiratory pressure at minimal respiratory elastance represents the best compromise between mechanical stress and lung aeration in oleic acid induced lung injury}, author={Alysson Roncally Silva Carvalho and Frederico C. Jandre and Alexandre V. Pino and Fernando A Bozza and Jorge I F Salluh and R. S. Rodrigues and F{\'a}bio Oliveira Ascoli and Antonio Giannella-Neto}, journal={Critical Care}, year={2007}, volume={11}, pages={R86 - R86} }