Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis.

@article{Kuo2012PositiveEO,
  title={Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis.},
  author={Jong-Jen Kuo and Hen-Hong Chang and Tung-Hu Tsai and Tzung-Yan Lee},
  journal={International journal of molecular medicine},
  year={2012},
  volume={30 3},
  pages={673-9}
}
Obesity contributes to the increased risk of liver- related morbidity and mortality. The accumulation of macrophages in adipose tissue in an inflammatory state is a hallmark of obesity-induced hepatic steatosis. In this study, we reveal the role of curcumin in the molecular mechanisms underlying inflammatory events in a model consisting of obese mice with hepatic steatosis. Obese mice fed with curcumin experienced significant weight loss and significantly reduced serum triglyceride (TG) levels… CONTINUE READING

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