Positive direct antiglobulin tests due to clavulanic acid.


Clavulanic acid, a beta-lactamase inhibitor, was found to be associated with the development of a positive direct antiglobulin test. Of 23 antibiotic courses in patients treated with ticarcillin, clavulanic acid, and tobramycin, 10 (43.5%) developed positive direct antiglobulin tests versus 2 of 26 (7.7%) patients treated with piperacillin and tobramycin (P… (More)


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@article{Williams1985PositiveDA, title={Positive direct antiglobulin tests due to clavulanic acid.}, author={Michael E. Williams and Dafydd J Thomas and Colleen P Harman and Paul D. Mintz and Gerald R. Donowitz}, journal={Antimicrobial agents and chemotherapy}, year={1985}, volume={27 1}, pages={125-7} }