Positive alterations of viscoelastic and geometric properties in ovariectomized rat femurs with concurrent administration of ibandronate and PTH.

@article{Yang2013PositiveAO,
  title={Positive alterations of viscoelastic and geometric properties in ovariectomized rat femurs with concurrent administration of ibandronate and PTH.},
  author={Xiao Yang and Padmalosini Muthukumaran and Shamal Dasde and Swee Hin Teoh and Hoon Choi and Sung-Kil Lim and Taeyong Lee},
  journal={Bone},
  year={2013},
  volume={52 1},
  pages={
          308-17
        }
}
Besides bone mineral density (BMD), structural and nano-level viscoelastic properties of bone are also crucial determinants of bone strength. However, treatment induced viscosity changes in osteoporotic bone have seldom been characterized. In this study, the effects of anabolic, antiresorptive and concurrent treatments on ovariectomized rat bones were thoroughly analyzed using multiple bone strength parameters. A total of 52 female Sprague-Dawley rats of 3 months age were divided into 5 groups… CONTINUE READING
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