Positive Natural Selection in the Human Lineage

@article{Sabeti2006PositiveNS,
  title={Positive Natural Selection in the Human Lineage},
  author={Pardis C. Sabeti and Stephen F. Schaffner and B. Fry and Jason Lohmueller and Patrick Varilly and O. Shamovsky and A. Palma and Tarjei Sigurd Mikkelsen and David Altshuler and Eric S. Lander},
  journal={Science},
  year={2006},
  volume={312},
  pages={1614 - 1620}
}
Positive natural selection is the force that drives the increase in prevalence of advantageous traits, and it has played a central role in our development as a species. Until recently, the study of natural selection in humans has largely been restricted to comparing individual candidate genes to theoretical expectations. The advent of genome-wide sequence and polymorphism data brings fundamental new tools to the study of natural selection. It is now possible to identify new candidates for… 
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