Positioning to get out of meiosis: the asymmetry of division.

@article{Brunet2011PositioningTG,
  title={Positioning to get out of meiosis: the asymmetry of division.},
  author={S. Brunet and Marie H{\'e}l{\`e}ne Verlhac},
  journal={Human reproduction update},
  year={2011},
  volume={17 1},
  pages={
          68-75
        }
}
BACKGROUND During meiosis, mammalian oocytes undergo two successive cell divisions without an intermediate replicative phase. This brief period, called 'meiotic maturation', is crucial for the formation of an egg capable of being fertilized and of generating viable and euploid offspring. METHODS We review our current knowledge of the cellular and molecular mechanisms that control asymmetry and appear to be shared between mammalian species, as well as the associated misfunctions that impair… Expand
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