Positioning mitochondrial plasticity within cellular signaling cascades.

  title={Positioning mitochondrial plasticity within cellular signaling cascades.},
  author={Vincent Soubannier and Heidi M McBride},
  journal={Biochimica et biophysica acta},
  volume={1793 1},
Mitochondria evolved from alpha-proteobacteria captured within a host between two and three billion years ago. This origin resulted in the formation of a double-layered organelle resulting in four distinct sub-compartments: the outer membrane, the intermembrane space, the inner membrane and the matrix. The inner membrane is organized in cristae, harboring the respiratory chain and ATP synthase complexes responsible of the oxidative phosphorylation, the main energy-generating system of the cell… CONTINUE READING