Positional information, in bits

  title={Positional information, in bits},
  author={Julien O. Dubuis and G. Tka{\vc}ik and E. Wieschaus and Thomas Gregor and W. Bialek},
  journal={Proceedings of the National Academy of Sciences},
  pages={16301 - 16308}
  • Julien O. Dubuis, G. Tkačik, +2 authors W. Bialek
  • Published 2013
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • Significance In a developing embryo, individual cells need to “know” where they are to do the right thing. How much do they know, and where is this knowledge written down? Here, we show that these questions can be made mathematically precise. In the fruit fly embryo, information about position is thought to be encoded by the concentration of particular protein molecules, and we measure this information, in bits. Just four different kinds of molecules are almost enough to specify the identity of… CONTINUE READING

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