Posaconazole concentrations in the central nervous system.

  title={Posaconazole concentrations in the central nervous system.},
  author={Maria J. G. T. R{\"u}ping and Nadine Albermann and Friedrich Ebinger and Irene Burckhardt and Claudia Beisel and Carsten H. G. M{\"u}ller and J{\"o}rg Janne Vehreschild and Matthias Kochanek and Gerd F{\"a}tkenheuer and Christopher Bangard and Andrew J Ullmann and Wolfgang Herr and Karin Kolbe and Michael J Hallek and Oliver A Cornely},
  journal={The Journal of antimicrobial chemotherapy},
  volume={62 6},
more susceptible to the killing activity of caspofungin. This study is the first comparing caspofungin killing activity against the closely related species C. parapsilosis, C. orthopsilosis and C. metapsilosis. Killing curves, regardless of the medium used, showed a decreasing order of susceptibility to caspofungin: C. metapsilosis . C. orthopsilosis . C. parapsilosis. Based on high echinocandin MICs for C. parapsilosis sensu stricto, in the case of isolates identified as C. parapsilosis sensu… CONTINUE READING


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Pharmacokinetics (PK) of oral posaconazole (POS) in neutropenic patients with acute myelogenous leukemia (AML)

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